解析与建构基因组 Systems Genetics - Applied in Biomedicine and Bioengineering Analysis and Construction of Genomes
21世纪,系统与合成生物学全球迅速发展,经历两次工业革命开发了矿物资源,将进入生物资源开发时代,堪称将产生第3次工业革命 - 医药与生物工业革命。20世纪90年代,曾(杰)邦哲发表系统医药学、系统生物工程与系统遗传学等概念,1994年(北京)率先开展转基因禽类输卵管生物反应器研发,并于2002年(德国)提出细胞通讯生物计算机模型。邦哲系统生物工程研究所有限公司,采取美国爱迪生从发明实验室到通用电气公司的产业化发展模式,应用系统遗传学 - 合成生物学技术,一是开发生物反应器与细胞计算机技术的生物工程产业化;二是开展重大疾病模型、天然药物筛选的生物医药资源开发。采用功能基因克隆与药物分子转基因表达、基因分析诊断与天然药物筛选等关键 高通量生物技术和计算机辅助设计技术,系统遗传学探讨生物进化、发育、病理、药理的非线性系统细胞发生动力学。 21st century, systems and synthetic biology is rapidly developing at worldwide. Experienced twice the industrial revolution of mineral resources development, the organism resources development will enter the era, and will produce the 3rd industrial revolution in medicine and bio-industrials. In 20th century 90's, the concepts of system genetics and applied in systems medicine, bioengineering, and transgenic avian used as oviduct bioreactor were published (B.J.Zeng, CAS, China), and the biocomputer model of cells communication (B.J. Zeng, FAL, Germany) was also put forward in 2002. Benjoe Institute of Systems Bio-Engineering Ltd., will take the industrial model of General Electric company developed from the Edison's invention laboratory. To study applied systems genetics - synthetic biology, the projects will be included at the aspects: 1). functional gene cloning, transgenic bioreactors and cell biocomputers, 2). genetic diagnosis, disease models and natural drug discovery. Use of high-through biotechnology and computer-aided design technology, systems genetics is investigated in the field of the non-linear cells system dynamics of evolution, development, pathology and pharmacology of organisms.
相关生物信息链接 合成生物技术平台 - 系统遗传学实验室 |