- CABSEs会议与FSMP论坛 -
国际系统生物学研究机构 (2) 系统生物学及其分支学科概念、词汇、理论和方法,在1999年之前均已经建立,诸多学派和学科的形成,经历20世纪比较沉静的发展历程,在21世纪伊始迅速兴起为潮流,构成一个完整学科的体系结构。 1925年美国A.J.洛特卡提出物理生物学,1929年E.B.Titchener发表“systematic psychology”,1958年Parry J.B.提出“systems psychology”,以及60年代的系统生态学和70年代的系统生理学等,这是早期的系统方法用于生物系统研究,1968年Mesarovic D.提出系统理论的“systems biology” - 1970年Rosen R.发展了系统分层的数学生物学,70年代免疫网络理论、生物化学和代谢系统论发展,80年代计算机方法用于数学建模,90年代基因差异表达分析、代谢工程等方法形成;因而,为世纪之交的系统生物学 – 遗传学、医学和生物工程的发展建立了基础,1999年,几乎是21世纪国际诸学派和分支学科和研究方向转折的文献起点 – 平行和同时,而后交汇,在2003年概念发生转换 – systems biology为理论与实验、计算方法整合的生物系统研究,1910年法国Leduc S.提出的“synthetic biology”转换为基于系统生物学的工程方法研究人工生物系统。 Systems Biology at Case http://systemsbiology.case.edu/sysbio/SysBio.shtml Systems Biology at Harvard https://sysbio.med.harvard.edu/ Chicago Center for Systems Biology http://chicago-center-for-systems-biology.org/ National Centers for Systems Biology http://www.systemscenters.org/ Cambridge Systems Biology Centre http://www.sysbiol.cam.ac.uk/index.php?page=dr-karen-lipkow Systems Biology Group, Univ. of Stuttgart Information Systems Biology http://www.systembiologie.de/en/information.html The ICREA-Complex Systems Lab Theoretical Systems Biology http://www.theosysbio.bio.ic.ac.uk/people/chris-barnes/ Center for Models of Life Computational Systems Biology of Cancer Group Computational Biology and Machine Learning Laboratory http://www.bio-complexity.com/index2.html Centre for Mathematical Medicine and Biology http://www.nottingham.ac.uk/cmmb/research/systems-medicine-and-biology.aspx Luxembourg Centre for Systems Biomedicine The Living Systems Revolution http://www.systemsrevolution.com/living-systems-medicine/what-is-living-systems-medicine/ Bioinformatics and Systems Medicine Laboratory Network Medicine,Scoop http://www.scoop.it/t/network-medicine Structural Bioinformatics and Network Biology Group http://sbnb.irbbarcelona.org/research Network Biology Research Laboratories Centre for Integrative Genetics (CIGENE) CISGen: Systems Genetics of Psychiatric Disorders http://compgen.unc.edu/ICASG/index.html Complex traits and systems genetics http://genetichealth.jax.org/personalized-medicine/our-contributions/complex-traits.html Systems Genetics at Oak Ridge National Laboratory http://www.ornl.gov/sci/ees/bsd/groups/mg.shtml Genomics and Systems Biotechnology Laboratory Design principles of biological circuits http://barkai-serv.weizmann.ac.il/GroupPage/ Synthetic Biology Science, Art and Film Festival Synthetic Biology community J. Craig Venter Institute Synthetic Biology,the Wyss Institute http://wyss.harvard.edu/viewpage/101/biomaterials-evolution Systems Biology for Energy and Environment http://genomicscience.energy.gov/ Institute of Systems & Synthetic Biology Systems & Synthetic Biology Applied Synthetic Biology in Europe http://www.efb-central.org/index.php/syntheticbiology/C58/ The synthetic biology initiative at NASA http://syntheticbiology.arc.nasa.gov/ (续前,仅为部分机构,列出提供一个学科体系比较全面的概貌。) (续)
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